Figure 1
From: Anti-biofilm activity of caffeine against uropathogenic E. coli is mediated by curli biogenesis
Effect of caffeine onantimicrobial activity,cell viability and growth kinetics profile of planktonic cells of CFT073 and K12MG1655: (a) MIC and MBIC determination of caffeine against CFT073 and K12 MG1655cellsin planktonic growth and their biofilms. (b) Effect of caffeine on the viability of CFT073 (c) Effect of caffeine on the viability of K12 MG1655. (d) Effect of caffeine on the growth of CFT073 bacteria grown in LB media supplemented with different concentrations of caffeine for 4 h. LB media without bacteria served as the negative control. CFT073 bacteria without caffeine served as the positive control. (e) Effect of caffeine on the growth of K12 MG1655 bacteria grown in LB media supplemented with different concentrations of caffeine for 4 h. LB media without bacteria served as the negative control. K12 MG1655 bacteria without caffeine served as the positive control. Optical Density at 600 nm was recorded every 15 min and the experiments were performed in triplicates. The data represents an average of three independent experiments presented as mean ± SD where *p < 0.05, **p < 0.01, ***p < 0.001,and ****p < 0.0001 indicates statistically significant difference relative to the untreated control (one-way ANOVA).
