Figure 7
From: Anti-biofilm activity of caffeine against uropathogenic E. coli is mediated by curli biogenesis

Effect of caffeine on E. coli curli genes expression (a) qRT-PCR results of curli-specific genes with caffeine (20 mM, 24 mM, 48 mM) treatment and without caffeine in E. coli CFT073 biofilms. (b) qRT-PCR results of curli-specific genes with caffeine (20 mM, 24 mM, 48 mM) treatment and without caffeine in E. coli K12 MG1655 biofilms. Error bar represents the mean ± SD of the samples performed in triplicates where **** indicates a statistically significant difference (p < 0.0001) relative to the untreated control (two-way ANOVA control; 0 μM).