Table 3 Association between urinary PGE-M levels and death, stratified by selected covariables.
From: Association of urinary prostaglandin E2 metabolite and mortality among adults
All-cause mortality | Died of cardiometabolic diseases | |||||
|---|---|---|---|---|---|---|
No. of deaths | HR (95% CI)* | P | No. of deaths | HR (95% CI)* | P | |
Gender | ||||||
Women | 253 | 1.15 (1.01, 1.31) | 0.035 | 173 | 1.25 (1.06, 1.46) | 0.007 |
Men | 108 | 1.21 (0.98, 1.49) | 0.076 | 74 | 1.32 (1.07, 1.63) | 0.010 |
P for interaction | 0.690 | 0.679 | ||||
Education levels | ||||||
< High school | 270 | 1.10 (0.97, 1.25) | 0.137 | 183 | 1.18 (1.02, 1.37) | 0.026 |
> = High school | 91 | 1.42 (1.13, 1.79 | 0.0026 | 64 | 1.52 (1.15, 2.00) | 0.003 |
P for interaction | 0.054 | 0.116 | ||||
NSAID use | ||||||
No | 321 | 1.21 (1.08, 1.36) | 0.00093 | 221 | 1.28 (1.12, 1.47) | 0.0003 |
Yes | 40 | 1.16 (0.76, 1.78) | 0.4777 | 26 | 1.12 (0.74, 1.71) | 0.585 |
P for interaction | 0.869 | 0.557 | ||||
Smoking status | ||||||
Never smoked | 291 | 1.20 (1.06, 1.35) | 0.0031 | 201 | 1.28 (1.11, 1.49) | 0.001 |
Ever smoked | 70 | 1.19 (0.91, 1.56) | 0.198 | 46 | 1.27 (0.97, 1.68) | 0.084 |
P for interaction | 0.908 | 0.963 | ||||
Age at sample collection | ||||||
< 60 | 35 | 2.24 (1.56, 3.23) | 1.0e-5 | 20 | 2.45 (1.47, 4.07) | 0.0006 |
> = 60 | 326 | 1.13 (1.00, 1.26) | 0.041 | 227 | 1.21 (1.06, 1.38) | 0.006 |
P for interaction | 0.0014 | 0.007 | ||||
WHR values | ||||||
< = 0.82 (median) | 111 | 1.14 (0.91, 1.42) | 0.261 | 77 | 1.2 5 (0.97, 1.62) | 0.091 |
> 0.82 (median) | 250 | 1.20 (1.06, 1.36) | 0.0048 | 170 | 1.27 (1.10, 1.48) | 0.001 |
P for interaction | 0.547 | 0.901 | ||||
Follow-up time | ||||||
During the first 5-year | 47 | 1.18 (0.89, 1.57) | 0.244 | 31 | 1.34 (0.96, 1.87) | 0.091 |
Between 5 and 10 years | 98 | 1.17 (0.97, 1.43) | 0.108 | 61 | 1.27 (1.00, 1.61) | 0.053 |
Over 10 years | 216 | 1.21 (1.05, 1.39) | 0.009 | 155 | 1.25 (1.06, 1.48) | 0.007 |
P for interaction | 0.971 | 0.945 | ||||
