Figure 4

Pathways leading to Eiger-Grnd/Wgn-mediated signaling collated from TNF-TNFR and Eiger-Wgn-mediated signaling pathways obtained from the KEGG database43,44,45 and validated using other sources46,47. Red stars represent the disrupted genes in the IndCh genome, purple star is the gene missing in IndCh but present in IndInt, blue stars are the missing pathway genes in all four assembled An. stephensi genomes. The inset table shows the status of the genes in all 4 strains (IndInt, IndCh, UCI and STE2) of An. stephensi for which a high-quality genome is available.