Table 2 Donor baseline characteristics for the study cohorts.
From: Enhanced survival prediction using explainable artificial intelligence in heart transplantation
N | Ext. validation 2017–2018 N = 4750 | Test 2014–2016 N = 6120 | Train/val. 1987–2013 N = 31,315 | Test statistic | |
|---|---|---|---|---|---|
Donor age (yrs)*,† | 42,185 | 24 31 40 33 ± 11 | 23 31 41 32 ± 11 | 21 30 42 32 ± 12 | F2 42182 = 18, P < 0.0012 |
Donor female gender* | 42,185 | 30%1443⁄4750 | 30%1828⁄6120 | 29%9214⁄31,315 | χ22 = 2.1, P = 0.361 |
Donor height (cm)* | 42,144 | 168.0 175.0 180.3 174.0 ± 9.6 | 167.6 175.0 180.3 173.8 ± 9.6 | 167.6 175.3 182.9 174.6 ± 9.5 | F2 42141 = 19, P < 0.0012 |
Donor weight (kg)* | 42,179 | 70 81 95 84 ± 19 | 70 80 93 83 ± 20 | 68 79 90 81 ± 18 | F2 42176 = 69, P < 0.0012 |
Donor ABO blood type* | 42,184 | χ26 = 7.7, P = 0.261 | |||
A | 36.7%1745⁄4750 | 35.3%2163⁄6120 | 36.4%11,413⁄31,314 | ||
AB | 2.1%99⁄4750 | 2.5%154⁄6120 | 2.3%706⁄31,314 | ||
B | 10.9%520⁄4750 | 11.3%690⁄6120 | 10.5%3295⁄31,314 | ||
O | 50.2%2386⁄4750 | 50.9%3113⁄6120 | 50.8%15,900⁄31,314 | ||
Donor cause of death* | 42,149 | χ28 = 2669, P < 0.0011 | |||
Anoxia | 38.2%1813⁄4748 | 29.8%1823⁄6118 | 12.3%3850⁄31,283 | ||
Cerebrovascular/stroke | 14.8%703⁄4748 | 19.1%1166⁄6118 | 25.6%8000⁄31,283 | ||
CNS tumor | 0.5%23⁄4748 | 0.3%21⁄6118 | 1.0%313⁄31,283 | ||
Head trauma | 44.6%2119⁄4748 | 48.6%2971⁄6118 | 59.3%18,544⁄31,283 | ||
Other | 1.9%90⁄4748 | 2.2%137⁄6118 | 1.8%576⁄31,283 | ||
Ischemic time (min)*,† | 40,394 | 138 184 223 183 ± 64 | 143 186 227 187 ± 62 | 146 188 229 190 ± 63 | F2 40391 = 23, P < 0.0012 |
Recipient-donor height ratio* | 42,037 | 0.963 1.000 1.036 1.000 ± 0.056 | 0.967 1.000 1.040 1.002 ± 0.057 | 0.958 1.000 1.036 0.998 ± 0.061 | F2 42034 = 16, P < 0.0012 |
Recipient-donor weight ratio* | 42,086 | 0.87 1.03 1.18 1.03 ± 0.23 | 0.88 1.02 1.17 1.03 ± 0.22 | 0.88 1.02 1.16 1.02 ± 0.21 | F2 42083 = 2.6, P = 0.0712 |
