Table 1 Top variants that have strong marginal associations in RET and NRG1.

From: Whole genome sequencing reveals epistasis effects within RET for Hirschsprung disease

Rs ID

Variant

MAF

p-value

RET

rs2506006

chr10:43581501:A:G

0.35

9.24E−43

rs2435357

chr10:43582056:T:C

0.35

1.66E−42

rs2435359

chr10:43580015:A:G

0.35

1.66E−42

NRG1

rs7005606

chr8:32401501:T:G

0.28

1.72E−09

rs6996585

chr8:32400803:A:G

0.28

2.88E−09

rs10090954

chr8:32402501:C:A

0.48

4.85E−08

  1. *rs2506006 is in high linkage disequilibrium with rs2435357 (r2 = 0.98).
  2. Variant column has the format of chromosomal position: alternative allele: reference allele.
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