Figure 1
From: Influence of tramadol on bacterial burden in the standard neutropenic thigh infection model
Bacterial burden in untreated and tramadol-treated groups in the neutropenic thigh infection model with two different inocula of E. faecalis. Bacterial burden expressed as cfu/g tissue was assessed for groups that were treated with either 20 mg/kg tramadol subcutaneously or left untreated (n = 9 per group). All groups were infected with E. faecalis at a low inoculum (1 × 107 cfu/ml, a-c) or at a high inoculum (1 × 108 cfu/ml, d-f). Bacterial burden was assessed in thigh (a,d), lung (b,e) and kidney (c,f). Statistical testing was performed using a Kolmogorov–Smirnov test. Ns not significant.
