Table 1 Characteristics and measured physiological parameters of the used axolotls.
Axolotl | Group A: Heart modeling/echo injections | Group B: Heart function | Group C: Evans blue injection | Group D: Oxygen consumption |
|---|---|---|---|---|
Number of animals in group | 3 | 4 | 2 | 6 |
Body mass (g) | 17.2 ± 6.3 | 35.1 ± 4.0 | 6.6 ± 0.28 | 63.7 ± 17.3 |
Total length (cm) | 13.0 ± 1.6 | 18.4 ± 0.3 | 9.8 ± 0.4 | 21.0 ± 2.3 |
Heart rate (beats/min) | 27.3 ± 6.4 (propofol) | 43.3 ± 0.5 (benzocaine) | 47.5 ± 6.4 (propofol) | 21.7 ± 4.1 (resting, unanesthetized) |
Ventricle volume (end diastole) (µl) | 130.5 ± 66.3 | |||
Ventricle volume (end systole) (µl) | 89.3 ± 57.5 | |||
Stroke volume (µl) | 33.1 ± 13.1 | 41.3 ± 8.5 | ||
Mass specific cardiac output (ml min−1 kg−1) | 52.3 ± 13.7 | 51.6 ± 14.3 | ||
Ventricle surface area (end diastole) (mm2) | 193.0 ± 64.4 | |||
Ventricle surface area (end systole) (mm2) | 154.8 ± 68.8 | |||
Ventricle sphericity (end diastole) (%) | 62.7 ± 1.4 | |||
Ventricle sphericity (end systole) (%) | 59.8 ± 2.0 | |||
Myocardial volume (µl) | 22.8 ± 6.2 | |||
Ejection fraction (%) | 46.8 ± 16.3 | |||
Oxygen consumption rate (ml min−1 kg−1) | 29.5 ± 5.9 |
