Table 2 Overview of the DILV patients.

From: Opportunities and short-comings of the axolotl salamander heart as a model system of human single ventricle and excessive trabeculation

 

Patient 1

Patient 2

Patient 3

Age (years)

52

16

56

Height (cm)

150

175

163

Weight (kg)

80

67

68

Sex

Female

Female

Female

Anatomic characteristics

Pulmonary vascular protection

Pulmonary stenosis

Restrictive VSD

No (Eisenmenger Syndrome)

Location hypoplastic ventricle

Right

Right

Left

Ventriculoarterial connection

Concordant

Concordant

Discordant

VSD restrictive

No

Yes

No

Functional characteristics

NYHA class

II

I

II

Heart rate at rest (beats min−1)

90

63

62

End-diastolic volume (ml; ml m−2)

204 (104)

236 (127)

261 (150)

End-systolic volume (ml; ml m−2)

92 (47)

99 (53)

103 (60)

Ejection fraction (%)

55

58

60

Stroke volume (ml)

112

137

158

Cardiac output (l min−1)

10.1

8.6

9.8

Mass specific cardiac output (ml min−1 kg−1)

126.3

128.4

144.1

Cardiac index (l min−1 m−2)

5.1

4.6

5.7

Systemic oxygen saturation at rest %

91

100

87

Peak oxygen consumption (ml O2 min−1 kg−1; % predicted)

6.3 (25)

31 (67)

13 (57)

RER

1.01

1.10

1.03

Laboratory measurements

Hemoglobin (mmol l−1)

13.9

8.7

12.9

Hematocrit (l l−1)

0.68

0.39

0.65