Table 3 Mortality rates and multivariable Cox regression of all-cause mortality in cancer patients with preexisting DM.

From: Additive interaction of diabetes mellitus and chronic kidney disease in cancer patient mortality risk

 

Subjects (n)

Events (n)

Person-years

Mortality

Rate

Model 1 (95% CI)

Model 2 (95% CI)

Overall

Male

Female

P for interaction

Overall

Male

Female

P for interaction

None

1,271

305

6,889

442.75

1 (Reference)

1 (Reference)

1 (Reference)

0.15

 1 (Reference)

 1 (Reference)

 1 (Reference)

 0.37

DKD

1,113

444

4,734

937.96

2.02

(1.75, 2.34)

1.85

(1.56, 2.18)

2.42

(1.79, 3.28)

 

1.55

(1.33, 1.81)

1.51

(1.27, 1.8)

1.7

(1.22, 2.37)

 
  1. *Abbreviations: BMI Body Mass Index, DM Diabetes Mellitus, DKD Diabetic Kidney Disease.
  2. *Mortality rate was calculated by dividing death cases by 10,000 person-years.
  3. *Model 1 is the unadjusted model; Model 2 is adjusted for age, sex, BMI, smoking status, alcohol consumption, history of hypertension, and cancer types.
  4. *P for interaction was tested by two-way interaction.
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