Figure 2 | Scientific Reports

Figure 2

From: Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning

Figure 2

Mean arterial pressure changes. Mean arterial pressure was measured over time in sham animals (Sham) and animals exposed to diisopropylfluorophosphate alone (DFP) with and without standard of care (SOC) treatment and/or the cell-permeable succinate prodrug NV354 (NV354). Time course analysis was performed using two-way ANOVA with Geisser-Greenhouse correction and Dunnett’s multiple comparison test with comparison to baseline (t0min). *p < 0.05; **p < 0.01 and p*** < 0.001 indicate significant difference. n = 6–7 per group.

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