Table 4 Analysis of factors associated with culture-confirmed sepsis among newborns at Hawassa University Comprehensive Specialized Hospital, Hawassa, Ethiopia February 2021 to November 2021.
From: Bacterial etiology and risk factors among newborns suspected of sepsis at Hawassa, Ethiopia
Variables | Culture result | COR (95% CI) | p value | AOR (95% CI) | p value | |
|---|---|---|---|---|---|---|
Positive (n = 143) (%) | Negative (n = 249) (%) | |||||
Place of delivery | ||||||
Home | 1 (16.7) | 5 (83.3) | 2.76 (0.318–23.851) | 0.351 | 1.47 (0.132–16.239) | 0.757 |
health center | 18 (48.7) | 19 (51.3) | 0.58 (0.294–1.149) | 0.119 | 0.45 (0.184–1.091) | 0.077 |
Hospital | 124 (35.5) | 225 (64.5) | 1 | 1 | ||
Gestational age | ||||||
Preterm | 41 (42.7) | 55 (57.3) | 1.42 (0.886–2.269) | 0.146 | 0.79 (0.425–1.458) | 0.446 |
Full term | 102 (34.5) | 194 (65.5) | 1 | 1 | ||
Premature rupture of membrane | ||||||
Yes | 63 (77.8) | 18 (22.2) | 10.10 (5.646–18.091) | < 0.001 | 12.70 (6.430–25.106) | < 0.001 |
No | 80 (25.7) | 231 (74.3) | 1 | 1 | ||
Way of delivery | ||||||
Spontaneous Virginal delivery | 68 (27.6) | 178 (72.4) | 1 | 1 | ||
Instrumental vaginal delivery | 32 (50) | 32 (50) | 0.38 (0.217–0.672) | 0.001 | 0.38 (0.192–0.782) | 0.008 |
Cesarean section | 43 (52.4) | 39 (47.6) | 0.35 (0.207–0.580) | < 0.001 | 0.42 (0.217–0.803) | 0.009 |
Sex of newborns | ||||||
Male | 88 (39.5) | 135 (60.5) | 1 | 1 | ||
Female | 55 (32.5) | 114 (67.5) | 1.35 (0.889–2.055) | 0.159 | 2.10 (1.214–3.560) | 0.008 |
Age of newborns in day | ||||||
≤ 7 | 76 (32.9) | 155 (67.1) | 1 | 1 | ||
≥ 8 | 67 (41.6) | 94 (58.4) | 0.72 (0.476–1.092) | 0.122* | 0.81 (0.464–1.428) | 0.473 |
APGAR score in5th min | ||||||
Low (< 7) | 43 (50.6) | 42 (49.4) | 1 | 1 | ||
Normal ( ≥) | 100 (32.6) | 207 (67.4) | 2.12 (1.301–3.451) | 0.003* | 1.24 (0.659–2.337) | 0.504 |
Reason for admission to NICU | ||||||
LBW | 30 (25.6) | 87 (74.4) | 3.63 (1.897–6.926) | < 0.001 | 3.17 (1.278–7.859) | 0.013 |
Hypothermia | 10 (27) | 27 (73) | 3.38 (1.401–8.132) | 0.007 | 1.88 (0.619–5.681) | 0.266 |
Sepsis | 29 (31.5) | 63 (68.5) | 2.72 (1.398–5.273) | 0.003 | 1.96 (0.839–4.565) | 0.120 |
Respiratory distress | 39 (47) | 44 (53) | 1.41 (0.730–2.723) | 0.306 | 2.76 (1.234–6.158) | 0.130 |
Prenatal asphyxia | 35 (55.6) | 28 (44.4) | 1 | 1 | ||
Respiratory support | ||||||
Absence of respiratory support | 38 (21.1) | 142 (78.9) | 3.95 (2.490–6.256) | < 0.001 | 3.53 (1.840–6.759) | < 0.001 |
Oxygen mask | 11 (37.9) | 18 (62.1) | 1.73 (0.773–3.862) | 0.182 | 2.63 (0.984–7.008) | 0.054 |
Nasal prong | 94 (51.4) | 89 (48.6) | 1 | 1 | ||
