Figure 3
From: The rate of microtubule breaking increases exponentially with curvature
Curvatures of all microtubule segments. (a) The complement of the cumulative distribution function of the curvatures of 0.5 μm microtubule segments for repeated experiments with 1 mM ATP, 500 μm−2 kinesin (Experiment 1: N = 107,107–blue; Experiment 2: N = 219,733–yellow; Experiment 3: N = 151,324–red, Experiment 4: N = 269,897–purple). The black solid line is the cumulative distribution of pooled data from the four individual experiments. The dashed black line indicates the expected curvature distribution for a persistent random walk with a 100 μm persistence length. (b) Curvature distributions found by Bicek et al.33 in motility assays (black) and living cells (red). (c) The segments of the pinned microtubules (red line) represent a fraction of all segments (black line, same as in a) which increases with curvature. The curvature distribution of only pinned microtubule segments is zero-padded to match the population size of all microtubule segments.
