Table 2 Protective role of GSE against KBrO3-induced genotoxicity.

From: Toxicity assessment of potassium bromate and the remedial role of grape seed extract

Abnormalities

Group I

Group II

Group III

Group IV

Group V

Group VI

MN

0.17 ± 0.41d

0.10 ± 0.32d

NDd

61.7 ± 5.36a

53.4 ± 4.85b

44.6 ± 4.12c

FRG

NDd

NDd

NDd

51.3 ± 4.74a

43.8 ± 4.10b

35.9 ± 3.88c

SC

0.30 ± 0.48d

0.20 ± 0.42d

0.16 ± 0.39d

43.5 ± 3.98a

35.7 ± 3.85b

28.6 ± 3.42c

VC

NDd

NDd

NDd

40.6 ± 3.95a

33.5 ± 3.66b

25.4 ± 3.18c

UDC

0.20 ± 0.42d

0.10 ± 0.32d

0.17 ± 0.39d

23.8 ± 2.94a

15.3 ± 1.67b

10.2 ± 1.33c

RP

NDd

NDd

NDd

18.0 ± 1.72a

12.4 ± 1.35b

8.10 ± 1.18c

NB

NDd

NDd

NDd

13.5 ± 1.36a

8.60 ± 1.22b

4.80 ± 0.64c

DM

NDd

NDd

NDd

8.30 ± 1.20a

5.20 ± 0.68b

2.90 ± 0.42c

  1. Group I: Control, Group II: 465 mg/L GSE, Group III: 930 mg/L GSE, Group IV: 100 mg/L KBrO3, Group V: 100 mg/L KBrO3 + 465 mg/L GSE, Group VI: 100 mg/L KBrO3 + 930 mg/L GSE. Values are shown as mean ± SD (n = 10). The MN and CAs numbers were calculated by analyzing 1.000 cells in each group. The averages shown with different letters(a-d) in the same line are significant at p < 0.05. MI: mitotic index, MN: micronucleus, FRG: fragment, SC: sticky chromosome, VC: vagrant chromosome, UDC: unequal distribution of chromatin, RP: reverse polarization, NB: nuclear bud, DM: disordered mitosis, ND: no data.