Table 4 Enzyme-linked immunosorbent assay (ELISA) of inflammatory chemokines.
From: Effect of teriparatide on drug treatment of tuberculous spondylitis: an experimental study
No (Control) | PTH | H37Rv | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | AVE | SEM | 1 | 2 | 3 | 4 | AVE | SEM | 1 | 2 | 3 | 4 | AVE | SEM | |
IL-8(pg/ml) | ||||||||||||||||||
Day 0 | 151.1 | 144 | 120.6 | 138.57 | 9.21 | 151.1 | 144 | 120.6 | 138.57 | 9.21 | 142.3 | 147 | 132.7 | 140.67 | 4.21 | |||
Day 1 | 206.7 | 197.3 | 325.6 | 319.1 | 262.18 | 34.82 | 205.7 | 199.4 | 337.9 | 339.9 | 270.73 | 39.38 | 232.7 | 231.5 | 329.6 | 324.2 | 279.50 | 27.39 |
Day 4 | 364.6 | 377.1 | 402.5 | 419.2 | 390.85 | 12.31 | 386.7 | 360.2 | 419.7 | 394.9 | 390.38 | 12.26 | 362.4 | 350.4 | 405 | 395.6 | 378.35 | 13.05 |
Day 7 | 367.6 | 348.6 | 373.6 | 361.6 | 362.85 | 5.34 | 350.4 | 338.2 | 385.7 | 361.6 | 358.98 | 10.11 | 208.8 | 210 | 337.5 | 349.5 | 276.45 | 38.79 |
MCP-1(pg/ml) | ||||||||||||||||||
Day 0 | 163.07 | 178.25 | 302.2 | 214.51 | 44.07 | 163.07 | 178.25 | 302.2 | 214.51 | 44.07 | 150.57 | 159.05 | 297.6 | 202.41 | 47.66 | |||
Day 1 | 503.34 | 520.36 | 345.3 | 359.1 | 432.03 | 46.30 | 551.13 | 501.88 | 351.7 | 349.4 | 438.53 | 51.78 | 530.75 | 531.68 | 328.6 | 316 | 426.76 | 60.36 |
Day 4 | 729.34 | 694.11 | 698.7 | 706.3 | 707.11 | 7.82 | 730.95 | 707.52 | 655.1 | 667.8 | 690.34 | 17.55 | 477.29 | 475.77 | 669.2 | 682.5 | 576.19 | 57.60 |
Day 7 | 550.77 | 515.54 | 587.7 | 549.5 | 550.88 | 14.74 | 552.38 | 528.95 | 614.7 | 609.6 | 576.41 | 21.21 | 298.71 | 297.2 | 688.9 | 676.6 | 490.35 | 111.11 |
IP-10(pg/ml) | ||||||||||||||||||
Day 0 | 3 | 2.4 | 4.5 | 3.30 | 0.62 | 3 | 2.4 | 4.5 | 3.30 | 0.62 | 2.5 | 2.9 | 5 | 3.47 | 0.78 | |||
Day 1 | 2.6 | 4.9 | 5 | 6.4 | 4.73 | 0.79 | 1.2 | 2 | 7.5 | 7.3 | 4.50 | 1.68 | 10.4 | 6.2 | 5.2 | 3.9 | 6.43 | 1.41 |
Day 4 | 24.7 | 24.6 | 33.5 | 40.1 | 30.73 | 3.76 | 25.3 | 28.3 | 40.3 | 38.9 | 33.20 | 3.76 | 1021.4 | 1025.8 | 1683.9 | 1593 | 1331.03 | 178.46 |
Day 7 | 353.4 | 359.3 | 488 | 494.6 | 423.83 | 39.00 | 401.6 | 394.1 | 494.8 | 493.5 | 446.00 | 27.84 | 1460.9 | 1467.8 | 2087.5 | 1995.3 | 1752.88 | 167.65 |
RANTES(pg/ml) | ||||||||||||||||||
Day 0 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0 | 0 | 0 | 0 | 0.00 | 0.00 |
Day 1 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0 | 0 | 0 | 0 | 0.00 | 0.00 |
Day 4 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 139.6 | 123.9 | 0 | 0 | 65.88 | 38.17 |
Day 7 | 555.2 | 526.3 | 277.14 | 255.12 | 403.44 | 79.62 | 611.7 | 622.8 | 243.36 | 282.86 | 440.18 | 102.57 | 952.3 | 920.4 | 764.5 | 786.77 | 855.99 | 47.07 |
H37Rv + PTH | H37Rv + INH + RFP | H37Rv + INH + RFP + PTH | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | AVE | SEM | 1 | 2 | 3 | 4 | AVE | SEM | 1 | 2 | 3 | 4 | AVE | SEM | |
IL-8(pg/ml) | ||||||||||||||||||
Day 0 | 142.3 | 147 | 132.7 | 140.67 | 4.21 | 142.3 | 147 | 132.7 | 140.67 | 4.21 | 142.3 | 147 | 132.7 | 140.67 | 4.21 | |||
Day 1 | 200.2 | 205.2 | 320.9 | 349.1 | 268.85 | 38.64 | 188.8 | 185 | 324.3 | 330 | 257.03 | 40.51 | 198.6 | 193.3 | 302.3 | 303.6 | 249.45 | 30.91 |
Day 4 | 338.3 | 362.4 | 387.4 | 395.3 | 370.85 | 12.92 | 339.9 | 346 | 408.8 | 411.8 | 376.63 | 19.49 | 342.2 | 359.9 | 424 | 423 | 387.28 | 21.23 |
Day 7 | 211.9 | 208.8 | 325.4 | 325.4 | 267.88 | 33.22 | 205.6 | 205.7 | 313.4 | 301.3 | 256.50 | 29.46 | 186.3 | 197.5 | 301.3 | 337.5 | 255.65 | 37.61 |
MCP-1(pg/ml) | ||||||||||||||||||
Day 0 | 150.57 | 159.05 | 297.6 | 202.41 | 47.66 | 150.57 | 159.05 | 297.6 | 202.41 | 47.66 | 150.57 | 159.05 | 297.6 | 202.41 | 47.66 | |||
Day 1 | 500.34 | 547.88 | 347.4 | 347.2 | 435.71 | 51.95 | 472.71 | 499.11 | 317 | 333.2 | 405.51 | 46.85 | 482.21 | 466.48 | 371.4 | 360.5 | 420.15 | 31.53 |
Day 4 | 501.57 | 494.55 | 662.4 | 674.3 | 583.21 | 49.24 | 489.07 | 481.98 | 644 | 628.2 | 560.81 | 43.61 | 469.09 | 495.73 | 685 | 685 | 583.71 | 58.73 |
Day 7 | 323 | 315.98 | 695.9 | 637.5 | 493.10 | 100.95 | 310.5 | 303.41 | 623.2 | 586 | 455.78 | 86.27 | 290.52 | 317.16 | 679.3 | 667.4 | 488.60 | 106.83 |
IP-10(pg/ml) | ||||||||||||||||||
Day 0 | 2.5 | 2.9 | 5 | 3.47 | 0.78 | 2.5 | 2.9 | 5 | 3.47 | 0.78 | 2.5 | 2.9 | 5 | 3.47 | 0.78 | |||
Day 1 | 17.1 | 10.2 | 4.3 | 4.4 | 9.00 | 3.03 | 9 | 11.4 | 5.3 | 7.5 | 8.30 | 1.28 | 4.8 | 5.6 | 3 | 6.2 | 4.90 | 0.70 |
Day 4 | 1252.7 | 1249.1 | 1865.7 | 1956.6 | 1581.03 | 191.50 | 196.3 | 195.7 | 264.4 | 261.1 | 229.38 | 19.28 | 155 | 155.9 | 247.4 | 237.6 | 198.98 | 25.21 |
Day 7 | 1412.8 | 1410.1 | 2257.6 | 2353.4 | 1858.48 | 258.83 | 937.9 | 909.1 | 718.9 | 715.6 | 820.38 | 59.83 | 908.4 | 931.8 | 701.9 | 692.2 | 808.58 | 64.60 |
RANTES(pg/ml) | ||||||||||||||||||
Day 0 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0 | 0 | 0 | 0 | 0.00 | 0.00 |
Day 1 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0 | 0 | 0 | 0 | 0.00 | 0.00 |
Day 4 | 127.6 | 120.9 | 0 | 0 | 62.13 | 35.89 | 332 | 321.3 | 0 | 0 | 163.33 | 94.32 | 262.2 | 263 | 0 | 0 | 131.30 | 75.81 |
Day 7 | 927.1 | 872.2 | 845.5 | 737.86 | 845.67 | 39.75 | 635.4 | 605.1 | 321 | 317.32 | 469.71 | 87.14 | 532.4 | 493.6 | 310.5 | 264.47 | 400.24 | 66.25 |