Figure 1
From: Global patterns of prognostic biomarkers across disease space
Trends for selected biomarkers hazard ratios across 209 diseases stratified by ICD10 class. Each dot represents a multivariate-adjusted CoxPH hazard ratio of a biomarker-disease association. Diseases are sorted from low to high risk within each ICD class with increased risk colored in red, and reduced risk colored in blue. The lowest and highest hazard disease within each class is labeled. Red Blood Distribution Width (RDW) is a risk factor for most diseases, Albumin is primarily associated with reduced risk across the whole disease space, and Glucose and low-density lipoprotein (LDL) showed mixed patterns. Diseases with the highest risk and lowest risk are marked by their ICD10 code. Elevated RDW is a predictor of iron deficiency anemia (D50). Elevated LDL is a risk factor for the development of acute myocardial infarction (I21). Elevated glucose is a risk for the development of insulin-dependent diabetes (E10).
