Figure 2

Behavioral and physiological data on weeks 2, 4, and 6 in all groups. (A–D) No differences were found in the open-field and rotarod test between the sham group and the remaining experimental groups. (E) and (F). No obvious changes in the heart rate and mean blood pressure parameters among the different groups. Sham, only suture the abdominal wall. pBDL, partial bile duct ligation surgery alone; ANES, repeated anesthesia in the pBDL model; MRI, repeated magnetic resonance imaging under anesthesia in the pBDL model; CE-MRI, repeated contrast-enhanced magnetic resonance imaging under anesthesia in the pBDL model.