Figure 1

Flowchart of recruitment. AT aerobic therapy, MT multimodal therapy, CT combination therapy, R randomized, P preference, T0: baseline, T1: after 10 weeks of intervention, T2: after 6 months, T3: after 4 years.
Flowchart of recruitment. AT aerobic therapy, MT multimodal therapy, CT combination therapy, R randomized, P preference, T0: baseline, T1: after 10 weeks of intervention, T2: after 6 months, T3: after 4 years.