Table 1 Overview of the composition of the GDC and 1000 Genomes datasets.
From: Pan-cancer functional analysis of somatic mutations in G protein-coupled receptors
GDC dataset (v 22.0) | 1000 Genomes dataset (2020) | |||||
|---|---|---|---|---|---|---|
Total subjects | 10,179 | 3202 | ||||
Total cancer types | 53 | n/a | ||||
Missense mutations | 2,129,235 | 2,943,276 | ||||
Missense mutations in GPCRs | ||||||
|---|---|---|---|---|---|---|
Class | Total | Unique | Unique receptors | Total | Unique | Unique receptors |
All class | 45,902 | 40,431 | 394 | 43,884 | 24,237 | 396 |
Class A | 26,342 | 23,122 | 284 | 20,528 | 11,454 | 286 |
Class B | 10,745 | 9588 | 47 | 15,439 | 8814 | 47 |
Class B1 | 1499 | 1342 | 15 | 2174 | 1283 | 15 |
Class B2 | 9246 | 8246 | 32 | 13,265 | 7531 | 32 |
Class C | 5592 | 4842 | 22 | 5273 | 2644 | 22 |
Class F | 1155 | 1039 | 11 | 487 | 368 | 11 |
Class T | 1675 | 1494 | 24 | 1639 | 719 | 24 |
Other GPCRs | 393 | 346 | 6 | 518 | 238 | 6 |
