Figure 3 | Scientific Reports

Figure 3

From: MDMX elevation by a novel Mdmx–p53 interaction inhibitor mitigates neuronal damage after ischemic stroke

Figure 3

K-181 attenuates acute ischemic stroke damage in mice. (A) Mice were orally administrated with K-181 (50 mg/kg) twice, 1 day before and immediately after tMCAO. (B,C) Representative TTC staining images (B) and quantification (C) of mice infarct size 2 days after tMCAO. N = 6. Scale Bar = 1 mm. (D,E) Representative images (D) and quantification (E) of mice cerebral blood flow visualized by Omegazone. N = 6. (F) Foot Faut test of mice 48 h after tMCAO. N = 5. (G) Neurological score of mice 48 h after tMCAO. N = 9.

Back to article page