Table 1 Characteristics of study participants with ISSNHL.

From: Association between atherosclerosis, hearing recovery, and hearing in the healthy ear in idiopathic sudden sensorineural hearing loss: a retrospective chart analysis

Characteristic

Count (%)a

N

762

Mean age, years (SD)

59.8 (15.1)

Sex

 Male

351 (46.1)

 Female

411 (53.9)

Affected ear

 Left

396 (52.0)

 Right

366 (48.0)

Current or past smoking, yes

236 (31.0)

Diabetes mellitus (DM)

131 (17.2)

Hypertension (HTN)

222 (29.1)

Hyperlipidemia (HLD)

182 (23.9)

Vascular disease

59 (7.7)

Venous thromboembolism (VTE)

8 (1.0)

Congestive heart failure (CHF)

17 (2.2)

Atrial fibrillation (Afib)

17 (2.2)

Stroke or transient ischemic attack (TIA)

27 (3.5)

Regular anticoagulant medication at onset of hearing loss, yes

28 (3.7)

Regular antiplatelet medication at onset of hearing loss, yes

74 (9.7)

Vertigo/Dizziness

225 (29.5)

PTA (dB) on affected side, mean (SD)

61.8 (23.0)

Initial MHLWb Grade of hearing loss, affected ear

 1

151 (19.8)

 2

226 (29.7)

 3

278 (36.5)

 4

107 (14.0)

Hearing loss

 Low frequencies

653 (85.7)

 Middle frequencies

717 (94.1)

 High frequencies

678 (89.0)

PTA (dB) on healthy ear, mean (SD)

24.7 (17.9)

Initial Grade of hearing loss, healthy ear

 0

483 (63.4)

 1

187 (24.5)

 2

53 (7.0)

 3

23 (3.0)

 4

16 (2.1)

Received systemic steroid therapy, yes

715 (93.8)

Received intratympanic steroid therapy (initial or salvage), yes

40 (5.2)

Latency to begin steroid treatmentc

 0–7 days post-onset

602 (79.0)

 8 or more days post-onset

160 (21.0)

Received prostaglandin E1 treatment, yes

131 (17.2)

Received hyperbaric oxygen therapy, yes

12 (1.6)

Hearing prognosis (outcome)

 Recovered

280 (36.7)

 Failed to recover

482 (63.3)

  1. SD, standard deviation; PTA, pure tone audiogram; PTA values represent the arithmetic mean of hearing threshold (measured in dB) obtained at 5 test frequencies (250, 500, 1000, 2000, 4000 Hz).
  2. aUnless otherwise indicated, values are counts (percentage); N represents patients who had unilateral ISSNHL and who had no evidence of vestibular schwannoma.
  3. bCriteria of the Sudden Deafness Research Committee of the Ministry of Health, Labour and Welfare.
  4. cSome patients never received steroid treatment; they were manually assigned to the 8-or-more-days group.