Figure 2

MiR-181b enhances chemosensitivity of NSCLC cells to DDP. (a) CCK analysis of IC50 values of DDP after transfected with miR-181b mimics, miR-181b inhibitors, or control in A549/DDP or A549 cell lines. (b) Flow cytometric analysis of cell cycle in A549/DDP and A549 were determined after transfected miR-181b mimics, miR-controls, miR-181b inhibitors or negative controls combined with DDP. (c) Flow cytometric analysis of apoptosis in A549/DDP and A549 were determined after transfected miR-181b mimics, miR controls, miR-181b inhibitors or negative controls combined with DDP. *P < 0.05; **P < 0.01; ***P < 0.001.