Figure 4
From: Role of cardiac mitofusins in cardiac conduction following simulated ischemia–reperfusion
Lateralization of Cx43 in the Mfn-DKO hearts. Cross-sections of left ventricle from 8-weeks-old males, (A) WT control versus (B) Mfn-DKO, cardiac-specific, transgenic mice, immuno-stained with anti-Cx43 (brown). Examples of lateralised regions of Cx43 are delineated with red arrows. The negative controls using normal rabbit IgG and secondary antibody solely, without primary antibody, are represented by (C,D) respectively. Scale bar = 20 µm (E) Quantitative analysis of Cx43 lateralization. Images are representatives of 3 hearts for each group. Data are presented as mean ± SEM; *p < 0.05 when compared against WT.
