Figure 6
From: Role of cardiac mitofusins in cardiac conduction following simulated ischemia–reperfusion
Schematic of murine atrial and ventricular isolation for MEA studies. Murine atrial tissue were placed epicardial surface down whereas transverse cross-section of the ventricle was emplaced onto the MEA for electrophysiological studies. Tissues were weighed down by a weighing harp. Representative electrograms recorded from a ventricular tissue slice using the MEA, with the proximal electrode (E1) and progressively distal electrodes (E2 and E3) to the paced stimulus. STIM indicates site of pacing stimulus, REF indicates the reference electrode position of the MEA. AT indicates activation time measured from stimulus onset to the steepest negative deflection of the electrogram. Created with BioRender.com”.
