Figure 8
From: Transcriptomic and proteomic pathways of diabetic and non-diabetic mitochondrial transplantation
Top 25 upregulated pathways implicated in the transcriptomic differences between hearts receiving diabetic and non-diabetic mitochondrial transplantation. (A) Venn diagram of overlapping top 25 MetaCore process networks shows commonality in muscle contraction and development of pathways enriched for hearts receiving diabetic ZDF- and non-diabetic ZL-mitochondrial transplantation compared to Vehicle. (B) Gene set enrichment analysis using MetaCore process networks of ZL vs ZDF mitochondria groups combined for 2 h and 28 days. (C) Gene set enrichment analysis using MetaCore localization analysis of ZL vs ZDF mitochondria groups combined for 2 h and 28 days.
