Table 3 Results for the assay of FAV and APX in human plasma.
Parameter | Spiked plasma samples | |||||||
|---|---|---|---|---|---|---|---|---|
Method (I) | Method (II) | |||||||
Amount taken (ng mL−1) | % Recovery* | Amount taken (ng mL−1) | % Recovery* | |||||
Mixture | FAV | APX | FAV | APX | FAV | APX | FAV | APX |
2 | 200 | 81.45 | 99.50 | 10 | 200 | 84.62 | 112.00 | |
4 | 400 | 116.95 | 101.00 | 20 | 400 | 106.05 | 100.25 | |
7 | 600 | 95.51 | 97.50 | 40 | 600 | 102.76 | 96.33 | |
10 | 800 | 97.09 | 102.63 | 60 | 800 | 100.28 | 98.00 | |
12 | 1000 | 102.17 | 99.10 | 80 | 1000 | 99.00 | 102.20 | |
Mean | 98.63 | 99.95 | 98.54 | 101.76 | ||||
± S.D | 12.80 | 1.95 | 8.23 | 6.14 | ||||
Slope | 73.32 | 302.00 | − 0.28 | 39.75 | ||||
Intercept | − 41.06 | 12.80 | − 0.59 | − 3.94 | ||||
Sy/x | 36.80 | 7.78 | 0.65 | 3.30 | ||||
Sa | 21.93 | 5.50 | 0.38 | 3.46 | ||||
Sb | 4.46 | 12.30 | 0.01 | 5.22 | ||||