Table 3 Results for the assay of FAV and APX in human plasma.

From: Conventional and synchronous spectrofluorometric determination of the recently administered drugs for treatment of COVID-19 favipiravir and apixaban

Parameter

Spiked plasma samples

Method (I)

Method (II)

Amount taken (ng mL−1)

% Recovery*

Amount taken (ng mL−1)

% Recovery*

Mixture

FAV

APX

FAV

APX

FAV

APX

FAV

APX

2

200

81.45

99.50

10

200

84.62

112.00

4

400

116.95

101.00

20

400

106.05

100.25

7

600

95.51

97.50

40

600

102.76

96.33

10

800

97.09

102.63

60

800

100.28

98.00

12

1000

102.17

99.10

80

1000

99.00

102.20

Mean

 

98.63

99.95

 

98.54

101.76

 ± S.D

12.80

1.95

8.23

6.14

Slope

73.32

302.00

− 0.28

39.75

Intercept

− 41.06

12.80

− 0.59

− 3.94

Sy/x

36.80

7.78

0.65

3.30

Sa

21.93

5.50

0.38

3.46

Sb

4.46

12.30

0.01

5.22

  1. *Each result is the average of three individual measurements.