Figure 4 | Scientific Reports

Figure 4

From: Humoral and cellular immune responses to Lassa fever virus in Lassa fever survivors and their exposed contacts in Southern Nigeria

Figure 4

T cell and antibody responses to LASV wane after a decade in LF survivors. Durability of both T cell response (positive specific interferon gamma ELISpot (a,b)) and antibody response (positive ELISA (c–f)) was measured by subtracting the time the patient was discharged from hospital (confirmed LASV negative RT-PCR test) from the time of sample collection (time in years) over 13 years. There was no T cell response after 8 years post-hospital discharge and IgG to both LASV GP and NP waned after eight years while IgM waned after 1 year post-infection. The table shows geometric mean at 95% CI. Statistical significance was calculated by Mann–Whitney test and p values are indicated. (Capped line with * indicating significance).

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