Figure 1 | Scientific Reports

Figure 1

From: COVID-19 plasma exosomes promote proinflammatory immune responses in peripheral blood mononuclear cells

Figure 1

Profiles of cytokine production in PBMCs treated with COVID-19 plasma exosomes. Heatmap of inflammatory cytokine antibody arrays (a, G7 slide; b, G8 slide, RayBiotech Inc.) using culture supernatants from PBMC treated with COVID-19 plasma exosomes derived from patients early in their admission (Pt0001E to Pt1620E) and the same patients later in their hospitalization (Pt0001L to Pt1620L). The average age of the patients was 70.4. PBMC were treated with exosomes (4 × 109 ml−1) for 16 h at 37 °C in RPMI media. (c) Principal components analysis plot of antibody array results. (d) Volcano plot of significantly expressed cytokines and chemokines based on the antibody arrays.

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