Figure 3
From: Neuronal deletion of CaV1.2 is associated with sex-specific behavioral phenotypes in mice
Neuronal CaV1.2 cKO mice have a deficit in associative learning. (a) Neuronal CaV1.2 cKO mice do not learn to leave on the light cue whereas CTRL mice do. We found a day × genotype interaction, and post hoc testing showed that cKO mice differed from CTRL mice on day 4. There were no sex-dependent effects. (b) Neuronal CaV1.2 cKO mice do not learn to avoid the air cue with trial initiation but CTRL mice do. There was a day × genotype interaction, and post hoc testing showed that cKO mice differed from CTRL mice on day 4. (c) There were no differences in how frequently mice walked onto the ladder before any cue was given, suggesting that mice did not display impulsive initiation of the task. Data are expressed as mean ± s.e.m, using ErasmusLadder 2.0.214, www.noldus.com/erasmusladder.
