Figure 5

DDR is involved in the regulation of RAR induced by heat-stress volatile signals. (A) Embryonic lethality of the top worms whose DNA damage checkpoint function (atm-1, clk-2, mrt-2, hus-1, and cep-1) is absent after coculture with the heat-stressed worms (N2); (B) Embryonic lethality of the top worms whose DNA repair function (HR, NHEJ , MMR, and NER) is absent after coculture with the heat-stressed worms (N2). Results are means ± SD (n = 5, *P < 0.05, **P < 0.01).