Figure 6 | Scientific Reports

Figure 6

From: Investigation into the communication between unheated and heat-stressed Caenorhabditis elegans via volatile stress signals

Figure 6

HSPs regulates the production of the heat-stress volatile signals in the bottom worms under heat stress. (A–C) Embryonic lethality of the top worms (N2) after coculture with heat-stressed bottom worms whose thermosensory neuron (gcy-8, gcy-23, and ocr-2), hsf-1, and HSPs functions are absent; (D) Proposed model of production and action of heat-stress volatile signals. Bottom worms sense heat stress by AFD and activate HSF-1. HSPs activate downstream related genes to produce heat-stress volatile signals. Top worms sense volatile stress signals by olfactory sensory neurons to activate DDR pathway (checkpoint, DNA repair, apoptosis) and induce RAR in meiotic and mitotic proliferating zone of gonad. Results are means ± SD (n = 5, **P < 0.01).

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