Table 6 Cross-over study design.

From: Effects of Aficamten on cardiac contractility in a feline translational model of hypertrophic cardiomyopathy

Subject and dose

Week 1

Cat 1–1 mg/kg

Cat 2 – 0.3 mg/kg

Cat 3–1 mg/kg

Cat 4 – 0.3 mg/kg

Week 2

Cat 5–Vehicle

Cat 6 – Vehicle

Cat 7 – 1 mg/kg

Cat 8 Vehicle

Week 3

Cat 1 – 0.3 mg/kg

Cat 2 – Vehicle

Cat 3 – Vehicle

Cat 4 – 1 mg/kg

Week 4

Cat 5 – 0.3 mg/kg

Cat 6 – 1 mg/kg

Cat 7 – 0.3 mg/kg

Cat 8 – 1 mg/kg

Week 5

Cat 1 – Vehicle

Cat 2 – 1 mg/kg

Cat 3 – 0.3 mg/kg

Cat 4—Vehicle

Week 6

Cat 5 – 1 mg/kg

Cat 6 – 0.3 mg/kg

Cat 7 – Vehicle

Cat 8 – 0.3 mg/kg

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