Figure 1

Whole blood IFN-γ responses after vaccination and challenge: The graph shows the IFN-γ levels measured by ELISA. Results are expressed as the increase in optical density (ΔOD 450 mn ± 95% CI). (a) Response against bovine tuberculin (PPD-B). (b) Response to the P22 complex. (c) Response against E/C antigen cocktail. *P < 0.05, **P < 0.01, Kruskal Wallis test with post hoc Dunn’s test. Groups: Control (n = 7, green), HIMB (n = 7, blue), HIMC (n = 7, red). Two animals of the control group were humanely sacrificed at week 7.