Figure 3

Whole brain [99mTc]HMPAO SPECT perfusion measured via a standardized uptake value (SUV) in 5XFAD (blue) and WT (green) mice at 11.5 ± 0.2 months of age. No significant differences in whole brain perfusion were observed between 5XFAD (0.372 ± 0.762) and WT (0.640 ± 0.955) mice (p = 0.536). Individual subjects are represented by colored circles and the bar plot indicates Mean ± SD.