Figure 1 | Scientific Reports

Figure 1

From: Cyperotundone combined with adriamycin induces apoptosis in MCF-7 and MCF-7/ADR cancer cells by ROS generation and NRF2/ARE signaling pathway

Figure 1

Effects of CYT and ADR on cytotoxicity and proliferation of MCF-7 and MCF-7/ADR cells. (a,b) CCK-8 assay showed that ADR inhibited the proliferation of MCF-7 and MCF-7/ADR cells (n = 6). (c,d) CCK-8 assay showed that CYT inhibited the proliferation of MCF-7 and MCF-7/ADR cells (n = 6). (e,f) ADR combined with CYT inhibited the proliferation of MCF-7 and MCF-7/ADR cells, as compared with the monotherapy group. The values are obtained from three independent experiments and shown as mean ± S.D. **p < .01. (g,h) The clone formation rates of the ADR, CYT, and ADR + CYT groups were lower than that of the control group, and the ADR + CYT group had the lowest rate in MCF-7 and MCF-7/ADR cells. The values are obtained from three independent experiments and shown as mean ± S.D. **p < .01.

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