Figure 4 | Scientific Reports

Figure 4

From: Cyperotundone combined with adriamycin induces apoptosis in MCF-7 and MCF-7/ADR cancer cells by ROS generation and NRF2/ARE signaling pathway

Figure 4

CYT combined with ADR Induced MCF-7 and MCF-7/ADR cells apoptosis by inhibiting the NRF2/ARE signaling pathways. (a) ADR + CYT reduced the expression levels of P62, NRF2, and HO-1 in MCF-7 cells and MCF-7/ADR cells. (b) The bar chart showed the mean ± S.D. of three experiments. β-actin was the internal control. (c) Brusatal promotes ADR + CYT-induced apoptosis in MCF-7 and MCF-7/ADR cells. (d) The bar chart showed the mean ± S.D. of three experiments.**p < .01.

Back to article page