Figure 4
Overlap between gene count data and pathways with an altered flow in the RISK dataset and enteroids: (A) Overlap between the reaction "families" that were found to be altered in the RISK dataset and enteroids. After conducting in silico RIPTiDe studies and performing random forest analysis, reactions involved in fatty acid oxidation were found to be altered in both the RISK dataset and the enteroids as detailed in Table 1. (B). Gene overlap between the RISK cohort and the ileal organoids- "enteroids." Gene count analysis showed that 99% of the genes present in enteroids were also present in the RISK dataset. Only 96 genes were found to be unique to the enteroids.
