Table 1 Monthly average of commercial units of antibiotics sold in Brazil for children aged 1–12 years, between 2014 and 2019 and during the pandemic period (Jan 2020 to July 2021).

	2014	2015	2016	2017	2018	2019	Pandemic	Sales Reduction (%)
Amoxicillin	460,879	485,696	514,597	586,303	576,264	603,683	186,655	65.3*
Azithromycin	137,195	149,734	165,952	186,835	188,782	198,973	110,989	35.1*
Cefalexin	101,731	108,492	119,554	116,504	111,688	112,854	73,262	34.4*
SXT	49,747	53,221	53,180	50,007	45,185	45,841	26,990	45.5*
Ceftriaxone	46,871	40,391	31,520	40,286	40,894	43,614	15,667	61.4*
Cefadroxil	13,542	12,943	12,330	11,870	11,063	10,947	5403	55.4*
Metronidazole	20,898	19,611	19,986	17,668	11,313	12,818	8834	48.1*
Levofloxacin	4,414	5,179	6,306	7,249	7376	6750	3990	35.7*
Penicillin G benzathine	2,445	2,908	5,088	3,836	2,644	3460	1847	45.6*
Erythromycin	6,823	5,364	3,856	2,786	225	8	1	99.9*
Total	806,137	883,539	932,369	1,023,344	995,434	1,038,948	433,637	54.1*

*Statistically significant reduction – (P < 0.0001). Dunnett Multiple Comparisons Test. SXT – (sulfamethoxazole and trimethoprim).

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