Table 1 Physical and laboratory measurements at baseline.

From: Efficacy and safety of sitagliptin treatment in older adults with moderately controlled type 2 diabetes: the STREAM study

Parameter

Sitagliptin

Control

P-value*

n

Mean (SD)

n

Mean (SD)

Age (year)

82

70.6 (3.9)

76

71.9 (4.4)

0.051

BMI (kg/m2)

69

24.9 (3.5)

63

24.7 (3.9)

0.73

SBP (mmHg)

77

131 (14)

71

132 (14)

0.73

DBP (mmHg)

77

73 (11)

71

70 (9)

0.08

FPG (mg/dL)

75

174 (54)

70

161 (53)

0.17

GA (%)

82

22.1 (3.8)

76

21.4 (3.0)

0.20

HbA1c (%)

82

7.8 (0.9)

76

7.6 (0.5)

0.08

Insulin (μU/mL)

75

9.6 (6.6)

70

8.1 (6.2)

0.16

Proinsulin (pmol/L)

74

33.9 (26.3)

69

28.5 (19.5)

0.17

Cr (mg/dL)

82

0.79 (0.21)

76

0.81 (0.23)

0.49

CysC (mg/L)

82

1.00 (0.23)

76

1.02 (0.23)

0.61

Cr-based eGFR

82

70 (17)

76

67 (16)

0.33

CysC-based eGFR

82

72 (18)

76

70 (15)

0.41

uACR (mg/g Cr)

82

176 (512)

76

114 (246)

0.33

T-C (mg/dL)

82

192 (43)

76

188 (37)

0.53

HDL-C (mg/dL)

82

55 (15)

76

54 (13)

0.79

LDL-C (mg/dL)

74

111 (35)

69

108 (34)

0.62

Non-HDL-C

82

138 (41)

76

134 (37)

0.58

Triglycerides (mg/dL)

75

141 (83)

70

142 (115)

0.98

  1. *Between-group differences based on unpaired t-test. BMI body mass index, Cr creatinine, CysC cystatin C, DBP diastolic blood pressure, eGFR estimated glomerular filtration rate (mL/min/1.73 m2), FPG fasting plasma glucose, GA glycated albumin, HDL-C HDL cholesterol, LDL-C LDL cholesterol, Non-HDL-C non-HDL cholesterol, SBP systolic blood pressure, T-C total cholesterol, uACR urinary albumin-creatinine ratio.