Figure 1 | Scientific Reports

Figure 1

From: Identification of TP53 mutations in circulating tumour DNA in high grade serous ovarian carcinoma using next generation sequencing technologies

Figure 1

Comparison of SNVs identified via Accel vs Oncomine in the plasma of HGSCO patients. (a) Bar graph denotes the SNVs and corresponding allele frequency (%) that are found by both ONCOMINE and ACCEL, ONCOMINE alone or ACCEL alone. Red line denotes the limit of detection (LOD) for the Accel NGS panel. (b) Correlation of the number of mutant copies derived from NGS (Oncomine, UMI) and ddPCR. Analysis was performed using Pearson’s correlation and P < 0.05 is considered significant.

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