Figure 3

Experimental in vitro data and optimally fitted ODE model. Dots represent the time course of ligand-induced G-protein subunit dissociation measured by FRET in HEK293 cells. FRET values were transformed into concentration of undissociated G-proteins by a scaling factor. Lines indicate the best-fit of the ODE model to the data (using optimal parameters). For methodological details, see Spahn et al.3.