Table 2 Correlation analysis of variables and microbiota characteristics of severe OSA.

	Anaerostipes		Peptoclostridium		Lachnoclostridium		Megamonas		Fusobacterium
	r	p	r	p	r	p	r	p	r	p
AHI (events/h)	− 0.484	0.012*	− 0.601	0.001*	0.368	0.064	0. 616	0.001*	0.606	0.001*
Mean SaO₂ (%)	0.445	0.023*	0.510	0.008*	− 0.426	0.030*	− 0.363	0.068	− 0.524	0.006*
Lowest SaO₂ (%)	0.480	0.013*	0.564	0.003*	− 0.445	0.023*	− 0.485	0.012*	− 0.596	0.001*
Glucose (mmol/L)	− 0.402	0.042*	− 0.104	0.611	0.312	0.120	0.162	0.429	0.093	0.651
TG (mmol/L)	− 0.123	0.548	− 0.426	0.030*	0.370	0.063	0.146	0.476	0.346	0.083
TCHO (mmol/L)	0.065	0.754	0.125	0.544	− 0.099	0.631	− 0.456	0.019*	− 0.088	0.668
HDL (mmol/L)	0.128	0.543	0.484	0.014*	− 0.435	0.030*	− 0.255	0.219	− 0.333	0.104
LDL (mmol/L)	0.065	0.757	0.089	0.671	− 0.106	0.615	− 0.443	0.027*	− 0.044	0.834
Leukocytes (10⁹/L)	0.048	0.815	− 0.378	0.057	0.085	0.679	0.219	0.282	0.150	0.465
Neutrophils (10⁹/L)	0.067	0.746	− 0.477	0.014*	0.123	0.550	0.128	0.534	0.253	0.211
Monocytes (10⁹/L)	− 0.206	0.313	− 0.470	0.015*	0.214	0.295	0.344	0.085	0.281	0.164
Lymphocytes (10⁹/L)	0.266	0.190	− 0.199	0.329	0.162	0.429	0.351	0.079	0.136	0.507
D-LA (mmol/L)	− 0.409	0.038*	− 0.491	0.011*	0.500	0.009*	0.408	0.039*	0.522	0.006*
I-FABP (pg/mL)	− 0.304	0.131	− 0.467	0.016*	0.266	0.189	0.247	0.223	0.241	0.236
BMI (Kg/m²)	− 0.313	0.120	− 0.644	< 0.001*	0.423	0.031*	0.545	0.020*	0.285	0.158

AHI, apnea hypoventilation index; M-SaO₂, Mean pulse oxygen saturation; L-SaO₂, Lowest pulse oxygen saturation; Glucose, fasting blood sugar; TG, triglycerides; TCHO, total cholesterol; HDL, high density lipoprotein; LDL, low-density lipoprotein; Leukocytes, white blood cell count; Neutrophils, neutrophil count; Monocytes, mononuclear cell count; Lymphocytes, lymphocyte count; D-LA, D-lactic acid; I-FABP, intestinal fatty acid-binding protein; BMI, body mass index.
p values based on Spearman analysis.
*P < 0.05, the difference is statistically significant.

Search