Table 1 Table of baseline characteristics, overall and stratified for MACE.

From: Comparison of cardiovascular biomarker expression in extracellular vesicles, plasma and carotid plaque for the prediction of MACE in CEA patients

 

Overall

No MACE

MACE

P

N

88

66

22

 

Age (mean (SD))

71.3 (7.5)

71.3 (7.3)

71.4 (7.9)

.95

Male (%)

68 (77.3)

51 (77.3)

17 (77.3)

1.00

BMI (mean (SD))

26.2 (3.4)

25.8 (3.4)

27.3 (3.2)

.11

Smoking (%)

36 (41.4)

26 (39.4)

10 (47.6)

.68

Pre-operative symptoms

.53

 Asymptomatic stenosis

19 (21.6)

15 (22.7)

4 (18.2)

 

 Ocular

15 (17.0)

9 (13.6)

6 (27.3)

 

 TIA

33 (37.5)

26 (39.4)

7 (31.8)

 

 Stroke

21 (23.9)

16 (24.2)

5 (22.7)

 

History of

 Peripheral intervention (%)

19 (21.6)

13 (19.7)

6 (27.3)

.65

 Coronary artery disease (%)

35 (39.8)

25 (37.9)

10 (45.5)

.71

 Stroke (%)

26 (29.5)

20 (30.3)

6 (27.3)

1.00

 Hypertension (%)

67 (76.1)

46 (69.7)

21 (95.5)

.030

 Diabetes Mellitus (%)

19 (21.6)

12 (18.2)

7 (31.8)

.30

Medication use of

 Insulin (%)

4 (4.5)

2 (3.0)

2 (9.1)

.26

 Glucose inhibitors (%)

18 (20.5)

11 (16.7)

7 (31.8)

.22

 Anticoagulants (%)

13 (14.8)

10 (15.2)

3 (13.6)

1.00

 Antiplatelets (%)

77 (87.5)

58 (87.9)

19 (86.4)

1.00

 Lipid lowering drugs (%)

62 (70.5)

48 (72.7)

14 (63.6)

.59

Laboratory results

 eGFR (mean (SD))

70.6 (20.1)

72.8 (21.0)

64.3 (15.7)

.084

 Triglycerides (median [IQR])

1.40 [1.04, 1.96]

1.41 [1.02, 1.92]

1.57 [1.09, 2.06]

.46

 LDL (mean (SD))

2.35 (0.95)

2.31 (0.889)

2.46 (1.11)

.51

 HDL (mean (SD))

1.09 (0.34)

1.11 (0.338)

1.03 (0.35)

.35

 Cholesterol (mean (SD))

4.20 (1.16)

4.17 (1.142)

4.27 (1.22)

.72

Plaque features

 Lipid core > 40%

25 (28.4)

18 (27.3)

7 (31.8)

.89

 Lipid core > 10%

62 (70.5)

46 (69.7)

16 (72.7)

1.00

 Collagen

72 (82.8)

54 (81.8)

18 (85.7)

.94

 Smooth muscle cell

58 (66.7)

43 (66.2)

15 (68.2)

1.00

 Intraplaque hemorrhage

56 (63.6)

42 (63.6)

14 (63.6)

1.00

 Macrophages

49 (57.0)

42 (64.6)

7 (33.3)

.024

 MAC mean (mean (SD))

0.855 (1.203)

0.892 (1.161)

0.746 (1.343)

.63

 SMC mean (mean ((SD))

2.013 (1.881)

2.084 (2.001)

1.814 (1.516)

.57

  1. BMI body mass index, TIA transient ischemic attack, eGFR estimated glomular filtration rate, LDL low-density lipoprotein, HDL high-density lipoprotein, MAC macrophages count, SMC smooth muscle cell, SD standard deviation, MACE major adverse cardiovascular events.
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