Table 4 The mechanism of antiviral action for the investigated indole and β-carboline indole alkaloids represented as viral inhibition (%) in a concentration-dependent manner.

From: Antiviral activities of plant-derived indole and β-carboline alkaloids against human and avian influenza viruses

Compound

Concentration (µg/ml)

Mechanism of Action

Viral replication (%)

Viricidal (%)

Viral adsorption (%)

Harmalol

0.1

87.5

41.5

60.3

1

96.9

50.9

74.5

10

98.7

58

82.1

Harmane

10

83.3

31.8

43.4

100

97.5

41.8

48.7

1000

96.7

82.1

61.4

Harmaline

1

28.3

91

34

10

40.3

96.7

46.2

100

48.7

98.6

51.8

Strychnine Sulfate

1

19.4

29.4

90.1

10

27.3

37

99.5

100

42

49.2

99