Table 1 Baseline demographic, clinical and anthropometric characteristics of the study patients.
Variables | NEPA + DEX1 (n = 76) | NEPA + DEX4 (n = 76) | P-value* |
---|---|---|---|
Age (years), mean (SD) | 64.4 (7.2) | 63.6 (7.9) | 0.45 |
Female sex, n (%) | 21 (27.6) | 22 (28.9) | 1.00 |
Weight (Kg), mean (SD) | 70.2 (13.5) | 72.5 (12.7) | 0.27 |
BMI (kg/m2), mean (SD) | 24.7 (4.1) | 25.4 (3.9) | 0.28 |
Healthy weight (18.5–24.9 kg/m2), n (%) | 43 (56.6) | 37 (48.7) | 0.69 |
Overweight (25–29.9 kg/m2), n (%) | 26 (34.2) | 30 (39.5) | |
Obese (≥ 30 kg/m2), n (%) | 7 (9.2) | 9 (11.8) | |
ECOG PS, n (%) | 0.22 | ||
0 | 63 (82.9) | 58 (76.3) | |
1 | 13 (17.1) | 18 (23.7) | |
Tumor stage, n (%) | 0.34 | ||
Early | 20 (26.3) | 16 (21.1) | |
Locally advanced | 27 (35.5) | 22 (28.9) | |
Metastatic | 29 (38.2) | 38 (50) | |
Alcohol intake, n (%) | 0.48 | ||
Never | 55 (72.4) | 50 (65.8)** | |
Everyday | 21 (27.6) | 26 (34.2) | |
Percentage WL in previous 6 months | |||
Mean (SD) | − 1.6 (5.5) | − 2.3 (5.1) | 0.39 |
***Pre-chemotherapy food intake, n (%) | 0.50 | ||
More than usual | 7 (9.2) | 11 (14.4) | |
Unchanged | 48 (63.2) | 42 (55.3) | |
Less than usual | 21 (27.6) | 23 (30.3) | |
BMI-adjusted WL grade, n (%) | 0.17 | ||
0 | 29 (38.2) | 28 (36.8) | |
1 | 23 (30.3) | 19 (25) | |
2 | 4 (5.2) | 14 (18.4) | |
3 | 15 (19.7) | 10 (13.2) | |
4 | 5 (6.6) | 5 (6.6) |