Table 2 Descriptive summary of pre-chemotherapy cancer-related symptoms by treatment group.
Symptoms | NEPA + DEX1 (n = 76) | NEPA + DEX4 (n = 76) | p-value* |
---|---|---|---|
Mean score (SD) for pain, (0–10 NRS) | 1.25 (2.3) | 1.68 (2.6) | 0.41 |
Pain (≥ 1 NRS), n (%) | 28 (36.8) | 32 (42.1) | 0.62 |
Significant pain (≥ 3 NRS), n (%) | 13 (17.1) | 18 (23.7) | 0.42 |
Mean score (SD) for tiredness, (0–10 NRS) | 2.14 (2.5) | 2.11 (2.7) | 0.70 |
Tiredness (≥ 1 NRS), n (%) | 45 (59.2) | 40 (52.6) | 0.51 |
Significant tiredness (≥ 3 NRS), n (%) | 29 (38.2) | 24 (31.6) | 0.50 |
Mean score (SD) for nausea, (0–10 NRS) | 0.33 (0.9) | 0.45 (1.5) | 0.98 |
Nausea (≥ 1 NRS), n (%) | 11 (14.5) | 11 (14.5) | 1.00 |
Significant nausea (≥ 3 NRS), n (%) | 3 (3.9) | 5 (6.6) | 0.72 |
Mean score (SD) for depression, (0–10 NRS) | 1.09 (1.7) | 1.21 (2.2) | 0.65 |
Depression (≥ 1 NRS), n (%) | 31 (40.8) | 26 (34.2) | 0.50 |
Significant depression (≥ 3 NRS), n (%) | 16 (21.1) | 14 (18.4) | 0.84 |
Mean score (SD) for anxiety, (0–10 NRS) | 1.43 (2.0) | 1.86 (2.7) | 0.92 |
Anxiety (≥ 1 NRS), n (%) | 39 (51.3) | 35 (46.1) | 0.63 |
Significant anxiety (≥ 3 NRS), n (%) | 17 (22.4) | 22 (28.9) | 0.46 |
Mean score (SD) for drowsiness, (0–10 NRS) | 1.76 (2.4) | 1.66 (2.5) | 0.41 |
Drowsiness (≥ 1 NRS), n (%) | 41 (53.9) | 32 (42.1) | 0.19 |
Significant drowsiness (≥ 3 NRS), n (%) | 20 (26.3) | 20 (26.3) | 1.00 |
Mean score (SD) for loss of appetite loss, (0–10 NRS) | 1.36 (2.4) | 1.57 (2.5) | 0.79 |
Loss of appetite (≥ 1 NRS), n (%) | 30 (39.5) | 30 (39.5) | 1.00 |
Significant loss of appetite (≥ 3 NRS), n (%) | 14 (18.4) | 19 (25) | 0.43 |
Mean score (SD) for well-being, (0–10 NRS) | 3.53 (2.7) | 3.82 (2.7) | 0.43 |
Poor well-being (≥ 1 NRS), n (%) | 63 (82.9) | 64 (84.2) | 1.00 |
Significant poor well-being (≥ 3 NRS), n (%) | 48 (63.2) | 49 (64.5) | 1.00 |
Mean score (SD) for difficulty of breathing, (0–10 NRS) | 1.11 (1.7) | 1.25 (2.0) | 0.88 |
Difficulty of breathing (≥ 1 NRS), n (%) | 32 (42.1) | 29 (38.2) | 0.74 |
Significant difficulty of breathing (≥ 3 NRS), n (%) | 15 (19.7) | 15 (19.7) | 1.00 |