Table 4 Crude and adjusted odds ratio for pregnancy, miscarriage and live birth.

From: A comprehensive analysis of chromosomal polymorphic variants on reproductive outcomes after intracytoplasmic sperm injection treatment

Outcome

Crude OR

Adjusted OR

Odds ratio (95% CI)

P

Odds ratio(95% CI)

P

Pregnancy

 Females, males or couples with polymorphic variations

1.08 (0.81–1.43)

0.58

1.09 (0.82–1.46)

0.52

 Non-acrocentric female only

0.98 (0.40–2.44)

0.98

0.83 (0.32–2.11)

0.70

 Acrocentric female only

0.72 (0.45–1.15)

0.17

0.74 (0.46–1.21)

0.23

 Non-acrocentric male only

1.20 (0.50–2.87)

0.68

1.34 (0.55–3.26)

0.51

 Acrocentric male only

1.30 (0.87–1.95)

0.19

1.29 (0.85–1.96)

0.22

 Both acrocentric & non-acrocentric male only

0.48 (0.05–4.15)

0.50

0.45 (0.04–4.07)

0.47

 Yqh in males

0.91 (0.39–2.12)

0.83

1.08 (0.46–2.56)

0.84

 Couples with non-acrocentric or acrocentric

1.33 (0.89–1.98)

0.15

1.36 (0.90–2.06)

0.13

Miscarriage

 Females, males or couples with polymorphic variations

1.17 (0.80–1.70)

0.40

1.19 (0.81–1.73)

0.36

 Non-acrocentric female only

1.34 (0.44–4.06)

0.60

1.25 (0.40–3.84)

0.69

 Acrocentric female only

0.94 (0.51–1.74)

0.86

0.97 (0.52–1.79)

0.93

 Non-acrocentric male only

0.60 (0.13–2.66)

0.51

0.64 (0.14–2.81)

0.55

 Acrocentric male only

1.26 (0.73–2.14)

0.39

1.26 (0.73–2.17)

0.39

 Both acrocentric & non-acrocentric male only

1.34 (0.15–11.6)

0.79

1.26 (0.14–11.1)

0.83

 Yqh in males

0.77 (0.22–2.63)

0.68

0.82 (0.23–2.82)

0.75

 Couples with non-acrocentric or acrocentric

1.48 (0.89–2.47)

0.12

1.51 (0.90–2.53)

0.11

Live Birth

 Females, males or couples with polymorphic variations

0.97 (0.69–1.38)

0.90

0.99 (0.69–1.42)

0.99

 Non-acrocentric female only

0.72 (0.21–2.50)

0.61

0.60 (0.17–2.13)

0.43

 Acrocentric female only

0.61 (0.32–1.15)

0.12

0.64 (0.33–1.21)

0.17

 Non-acrocentric male only

1.69 (0.65–4.42)

0.27

2.00 (0.75–5.32)

0.16

 Acrocentric male only

1.22 (0.75–2.00)

0.41

1.21 (0.73–2.00)

0.45

 Yqh in males

1.06 (0.39–2.87)

0.90

1.36 (0.49–3.76)

0.55

 Couples with non-acrocentric or acrocentric

1.07 (0.65–1.78)

0.76

1.08 (0.65–1.81)

0.74

  1. The reference category is no chromosomal polymorphic variations in either partner.
  2. There were no pregnancies, miscarriages or live births recorded in both non-acrocentric and acrocentric female only groups.
  3. There were no live births recorded in both non-acrocentric and acrocentric male only group.
  4. Reproductive outcomes are adjusted for confounding variables including age, BMI, serum FSH, LH levels, and type of treatment.
  5. OR Odds ratio.
  6. CI 95% Confidence interval.
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