Figure 4 | Scientific Reports

Figure 4

From: Fetal growth restriction followed by early catch-up growth impairs pancreatic islet morphology in male rats

Figure 4

Representative photographs of pancreatic islets from 36-week-old male and female rats immunostained with an anti-insulin antibody and counterstained with hematoxylin and eosin at an original magnification of 400 × . (a) Islets of male FGR-GN rats exhibited a dysmorphic structure, large size, and scattered islet tissues. (b) Islets of female FGR-GN rats. (c) Islets of male FGR-PN rats showed slight dysmorphisms. The islets appeared normal in female FGR-PN rats (d) and in male and female sham-GN and sham-PN rats (e–h). Scale bars indicate 200 µm. The number of male offspring: sham-GN: n = 6, sham-PN: n = 7, FGR-PN: n = 8, and FGR-GN: n = 7. Number of female offspring: sham-GN: n = 7, sham-PN: n = 8, FGR-PN: n = 7, and FGR-GN: n = 8. FGR: fetal growth restriction, GN: good nutrition, PN: poor nutrition.

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