Table 3 Height outcome in subjects with GnRHa treatment or GnRHa + GH treatment.

From: Effect of gonadotropin-releasing hormone agonist monotherapy and combination therapy with growth hormone on final adult height in girls with central precocious puberty

Variable

GnRHa (n = 188)

GnRH + GH (n = 22)

P-value

During treatment

 Δ PAH*

9.90 ± 5.86

13.66 ± 6.39

0.005

 Growth velocity (cm/year)

5.29 ± 5.86

6.40 ± 0.85

 < 0.001

From end of GnRHa to final adult height

 Total growth (cm)

11.79 ± 5.86

11.74 ± 2.70

0.937

Final adult height

 Height gain (FAH- initial PAH) cm

4.72 ± 5.01

9.22 ± 6.03

 < 0.001

 Genetic height gain (FAH-TH) cm

2.04 ± 4.75

0.69 ± 3.53

0.199

  1. GnRHa Gonadotropin-releasing hormone agonist, GH Growth hormone, PAH predicted adult height-calculated with advanced table of baley–Pinneau(BP)method, FAH Final adult height, TH Target height.
  2. *Δ PAH: the difference between PAH at the end of treatment and initial PAH.
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