Figure 1 | Scientific Reports

Figure 1

From: A fragment of type VI collagen alpha-6 chain is elevated in serum from patients with atopic dermatitis, psoriasis, hidradenitis suppurativa, systemic lupus erythematosus and melanoma

Figure 1

Overview of type VI collagen, the target of C6A6 and assay specificity. (A) The primary structure of type VI collagen including domains from all six alpha-chains, (B) Sequence alignment of the targeted COL6Α6 sequence in human, mouse, bovine and rat species (black box). The sequence was aligned using Uniprot, (C) Specificity of the C6A6 assay. Reactivity towards the standard peptide (DSGPEYADVV), truncated peptide (SGPEYADVV), elongated peptide (QDSGPEYADVV) and non-sense standard peptide (YRDDLKKLLE). No background signal was detected when coating with a non-sense coating peptide (YRDDLKKLLE-Biotin). Signals are shown as relative luminescence (RLU) per second, as a function of standard peptide.

Back to article page